Biological Blood Residue contamination on surface before laser cleaning
Ikmanda Roswati
Ikmanda RoswatiPh.D.Indonesia
Ultrafast Laser Physics and Material Interactions
Published
Dec 16, 2025

Biological Blood Residue Contamination

Blood-residue contamination, it arises from biological sources like proteins and hemoglobin. When blood contacts surfaces, drying happens quickly and sticky layers form, thus oxidation and coagulation harden them over time. This residue embeds into microstructures rapidly after exposure, and unique reddish-brown staining with fluorescence under lights distinguishes it from inorganic dust or oils. Behavior on materials varies thus. On stainless steel, residue adheres firmly and causes corrosion, while crown glass and float glass suffer cracking from penetration. Borosilicate glass resists bonding deeper, yet fused silica and Gorilla glass still trap it in pores, so alumina and silicon carbide hold it in rough textures. Key challenges emerge in removal, tenacity demands aggressive methods and risks damage, solvents fail to dissolve bonds so contamination lingers in crevices. Laser cleaning addresses this effectively, pulses target organic bonds precisely and ablation vaporizes residues without heat spread, thus surfaces exhibit cleanliness and integrity preserves.

Safety Information

Critical safety data for laser removal operations

Fire/Explosion Risk
low
Toxic Gas Risk
moderate
Visibility Hazard
moderate

Required Personal Protective Equipment

Respiratory Protection
PAPR
Eye Protection
goggles
Skin Protection
full_suit

Hazardous Fumes Generated

CompoundConcentrationExposure LimitHazard ClassStatus
Carbon Monoxide5 mg/m³29 mg/m³toxic✓ Within Limit
Hydrogen Cyanide1.5 mg/m³5 mg/m³toxic✓ Within Limit
Benzene0.8 mg/m³1.6 mg/m³carcinogenic✓ Within Limit
Formaldehyde0.5 mg/m³0.37 mg/m³carcinogenic⚠️ Exceeds Limit
Acrolein0.1 mg/m³0.23 mg/m³irritant✓ Within Limit

Ventilation Requirements

Air Changes Per Hour
12
Exhaust Velocity
0.5 m/s
Filtration Type
HEPA

Particulate Generation

Respirable Fraction
70%
Size Range
0.1 - 10 μm

Substrate Compatibility Warnings

  • Laser parameters must be carefully controlled to prevent surface damage to underlying material
  • Biohazard containment required for all generated aerosols and debris