

Ikmanda RoswatiPh.D.Indonesia
Ultrafast Laser Physics and Material InteractionsPublished
Dec 16, 2025
Pharmaceutical Drug Residue Contamination
Pharmaceutical-residue contamination, it arises from active ingredient deposits during equipment processing. This residue, it forms sticky layers and differs from mineral scales by organic stickiness that bonds deeply. On stainless steel and glass, it clings unevenly and defies solvents, so removal challenges persist; laser cleaning, it vaporizes residue selectively and leaves surfaces intact.
Safety Information
Critical safety data for laser removal operations
Fire/Explosion Risk
low
Toxic Gas Risk
moderate
Visibility Hazard
moderate
Required Personal Protective Equipment
Respiratory Protection
PAPR
Eye Protection
goggles
Skin Protection
gloves
Hazardous Fumes Generated
| Compound | Concentration | Exposure Limit | Hazard Class | Status |
|---|---|---|---|---|
| Pyrolytic Carbon Particles | 5-50 mg/m³ | 3 mg/m³ | toxic | ✓ Within Limit |
| Carbon Monoxide | 10-100 mg/m³ | 29 mg/m³ | toxic | ✓ Within Limit |
| Polycyclic Aromatic Hydrocarbons (PAHs) | 0.1-2 mg/m³ | 0.2 mg/m³ | carcinogenic | ✓ Within Limit |
| Volatile Organic Compounds (VOCs) | 5-30 mg/m³ | 50 mg/m³ | toxic | ✓ Within Limit |
Ventilation Requirements
Air Changes Per Hour
12
Exhaust Velocity
0.5 m/s
Filtration Type
carbon
Particulate Generation
Respirable Fraction
80%
Size Range
0.01 - 10 μm
Substrate Compatibility Warnings
- •Laser parameters must be optimized to prevent substrate damage and excessive pyrolysis
- •Residue composition may vary significantly between pharmaceutical products
- •Potential for secondary contamination of surrounding surfaces

